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1620 ( MDCXX) was a leap year starting on Wednesday of the Gregorian calendar and a leap year starting on Saturday of the Julian calendar, the 1620th year of the Common Era (CE) and (AD) designations, the 620th year of the Anno Domini 2nd millennium, the 20th year of the 17th century, and the 1st year of the 1620s decade. As of the start of 1620, the Gregorian calendar was 10 days ahead of the Julian calendar, which remained in localized use until 1923.
July 25 (July 15 OS) – The armed merchant ship embarks about 65 emigrants for New England at or near her home port of Mayflower Rotherhithe on the Thames east of London; about July 29 (July 19 OS) she anchors in Southampton Water. 
August 1 (July 22 OS) – The ship departs Speedwell Delfshaven with English separatist Puritans from Leiden bound to rendezvous with the ; on August 5 (July 26 OS) she anchors in Southampton Water. Mayflower 
August 15 (probable date; August 5 OS) – and Mayflower depart together from Southampton, Speedwell but are forced to put back into  Dartmouth, Devon, for repairs to a leak in the latter ship on August 22 or 23 (August 12 or 13 OS).
September 2 (August 23 OS) – and Mayflower depart together from Dartmouth; they are well out into the Atlantic when the Speedwell Speedwell is again found to be leaking. 
September 7 (August 28 OS) – Mayflower and return again to England, anchoring at Speedwell Plymouth; the latter ship is given up as a participant in the voyage and on September 12 (September 2 OS) departs for London with most of her passengers and stores having been transferred to the Mayflower. 
September 16 (September 6 OS) – departs from Mayflower Plymouth in England on her third attempt to cross the Atlantic. The  Pilgrims onboard comprise 41 "saints" (English separatists largely from Holland), 40 "strangers" (largely secular planters from London), 23 servants and hired workers, together with c. 30 crew.
September 17– October 7 – Battle of Cecora: The Ottoman Empire defeats Polish-Lithuanian Commonwealth- Moldavian troops.
October 6 – Battle of Amedamit in Gojjam, Ethiopia: The Roman Catholic Ras Sela Kristos, half-brother of Emperor Susenyos, crushes a group of rebels, who were opposed to Susenyos' pro-Catholic beliefs.
November 3 – The Great Patent is granted to Plymouth Colony.
November 8 – Thirty Years' War: Battle of White Mountain – Catholic forces are victorious in only two hours near Prague.
November 21 (November 11 OS) – The arrives inside the tip of Mayflower Cape Cod (named from the Concord voyage of 1602), at what becomes known as Provincetown Harbor, with the Pilgrims and Planters; 41 Plymouth Colony settlers sign the Mayflower Compact, the first governing document of the colony, onboard the ship.
November 25 – The Wedding of Gustav II Adolf and Maria Eleonora takes place. December 21 – Plymouth Colony: William Bradford and the Mayflower Pilgrims land on what becomes known as Plymouth Rock, in Plymouth, Massachusetts.
January 5 – Miklós Zrínyi, Croatian military commander (d. 1664)
January 9 – Anton Günther I, Count of Schwarzburg-Sondershausen (d. 1666)
January 17 – Anton Janson, Dutch type founder and printer (d. 1687)
January 31 – Prince Georg Friedrich of Waldeck, Dutch general and German field marshal (d. 1692)
February 1 – Gustaf Bonde, Swedish politician (d. 1667)
February 3 – Sir James Clavering, 1st Baronet, English landowner (d. 1702)
February 5 – Paul Barbette, Dutch physician (d. 1666)
February 13 – Girolamo Casanata, Italian cardinal (d. 1700)
February 15 – François Charpentier, French archaeologist and man of letters (d. 1702)
February 16 – Frederick William, Elector of Brandenburg (d. 1688)
February 23 – Francis Newport, 1st Earl of Bradford, English politician (d. 1708)
March 10 – Johann Heinrich Hottinger, Swiss philologist and theologian (d. 1667)
March 13 – Alexander Seton, 1st Viscount of Kingston (d. 1691) March 29 – Edward Digges, English barrister and colonist, Colonial Governor of Virginia (d. 1674)
April 4 – Bernardino León de la Rocha, Roman Catholic prelate, Bishop of Coria and of Tui (1669-1673) (d. 1675)
April 15 – Edward Villiers, English politician and military officer (d. 1689)
April 17 – Marguerite Bourgeoys, French Catholic nun, founder of the Congregation of Notre Dame (d. 1700)
April 18 – Winston Churchill (1620-1688), English noble, soldier (d. 1688)
April 21 – Salvatore Castiglione, Italian painter (d. 1676)
April 24 – John Graunt, English demographer (d. 1674)
May 3 – Bogus?aw Radziwi, Polish-Lithuanian noble (d. 1669)
May 21 – Krsto Zmajevi?, Montenegrin-born Venetian merchant (d. 1688)
May 23 – Pieter Neefs the Younger, Flemish painter (d. 1675)
May 25 – Warwick Mohun, 2nd Baron Mohun of Okehampton, English Member of Parliament (d. 1665)
June 6 – Sir John Covert, 1st Baronet, English politician (d. 1679) June 11 – John Moore (Lord Mayor), Member of Parliament for the City of London (d. 1702)
July 21 – Jean Picard, French astronomer and priest (d. 1704)
July 31 – Juan Ignacio de la Carrera Yturgoyen, Chilean politician (d. 1682)
August 6 – William Hiseland, English (later British) soldier, reputed supercentenarian (d. 1732)
August 19 – Johann Just Winckelmann, German writer and historian (d. 1699)
August 22 – Alexander Rigby (died 1694), English politician (d. 1694)
August 24 – Thomas Stucley (MP), English politician (d. 1663)
August 26 – Ernst Bogislaw von Croÿ, German Lutheran administrator (d. 1684)
September 4 – Ernest Gottlieb, Prince of Anhalt-Plötzkau (d. 1654)
September 6 – Isabella Leonarda, Italian composer (d. 1704)
September 18 – Albert II, Margrave of Brandenburg-Ansbach, German prince (d. 1667)
September 25 – François Bernier, French physician and traveller (d. 1688) September 29 – John Louis of Elderen, Bishop of Liege (d. 1694)
October 1 – Nicolaes Pieterszoon Berchem, Dutch Golden Age painter of pastoral landscapes (d. 1683)
October 4 – François-Henri Salomon de Virelade, French lawyer (d. 1670)
October 15 – William Borlase (died 1665), English politician (d. 1665)
October 16 – Pierre Paul Puget, French painter (d. 1694)
October 20 – Aelbert Cuyp, Dutch painter (d. 1691)
October 27 – Philip Louis, Duke of Schleswig-Holstein-Sonderburg-Wiesenburg (d. 1689)
October 31 – John Evelyn, English diarist and writer (d. 1706)
c. November 20 – Peregrine White, first child born to English settlers at Plymouth Colony (d. 1704)
December 18 – Heinrich Roth, German Jesuit missionary, pioneering Sanskrit scholar (d. 1668) December 23 – Johann Jakob Wepfer, Swiss pathologist (d. 1695)
Worden, Nigel; Van Heyningen, Elizabeth; Bickford-Smith, Vivian. Cape Town – the Making of a City: an Illustrated Social History . Retrieved 2007.
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Ames, Azel (1901). . Boston: Houghton Mifflin The May-Flower and Her Log . Retrieved 2019.
Williams, Hywel (2005). . London: Weidenfeld & Nicolson. Cassell's Chronology of World History ISBN . 0-304-35730-8
Stratton, J. M. (1969). Agricultural Records. John Baker. ISBN . 0-212-97022-4
"Mirror of the Cruel and Horrible Spanish Tyranny Perpetrated in the Netherlands, by the Tyrant, the Duke of Alba, and Other Commanders of King Philip II". World Digital Library. 1620 . Retrieved 2013.
Pavel, Lilia Zabolotnaia (2012). "The Story of the Courtship of Catherine 'the Circassian', the Second Wife of the Prince Vasile Lupu" (PDF). Codrul Cosminului. 18 (1): 43-50 . Retrieved 2015.
Inachim, Kyra (2008). "Herrschaft der letzten Greifengeneration". Die Geschichte Pommerns (in German). Rostock: Hinstorff. ISBN . 978-3-356-01044-2