|Antiochus II Theos|
Coin of Antiochus II.
|Basileus of the Seleucid Empire|
|Reign||2 June 261 - July 246 BC|
|Predecessor||Antiochus I Soter|
|Successor||Seleucus II Callinicus|
|Died||early July 246 BC (aged 39-40)|
|Issue||with Laodice: |
Seleucus II Callinicus
Stratonice of Cappadocia
|Father||Antiochus I Soter|
|Mother||Stratonice of Syria|
Antiochus II Theos (Greek: ? ?; 286 - July 246 BC) was a Greek king of the Hellenistic Seleucid Empire who reigned from 261 to 246 BC. He succeeded his father Antiochus I Soter in the winter of 262-61 BC. He was the younger son of Antiochus I and princess Stratonice, the daughter of Demetrius Poliorcetes.
He inherited a state of war with Ptolemaic Egypt, the "Second Syrian War", which was fought along the coasts of Asia Minor, and the constant intrigues of petty despots and restless city-states in Asia Minor. Antiochus also made some attempt to get a footing in Thrace. During the war he was given the title Theos (Greek: ?, "God"), being such to the Milesians in slaying the tyrant Timarchus.
During the time Antiochus was occupied with the war against Egypt, Andragoras, his satrap in Parthia, proclaimed independence. According to Justin's epitome of Pompeius Trogus, in Bactria, his satrap Diodotus also revolted in 255 BC, and founded the Greco-Bactrian Kingdom, which would further expand in India in 180 BC to form the Indo-Greek Kingdom (180-1 BC).
In 253 BC, in the aftermath of the Second Syrian War, Antiochus II made peace with the pharaoh Ptolemy II Philadelphus. He divorced Laodice and married Ptolemy II's daughter Berenice, with the understanding that any children born from their union would inherit the Seleucid throne. Although no longer queen, Laodice was still a very powerful and political influential figure. Antiochus gave Laodice various land grants throughout Anatolia which are known through inscriptions; she owned a large estate in the Hellespont, other properties near Cyzicus,Ilion and in Caria. In a royal record at Sardis mentions her land titles were to be kept as royal land in disposal in grants or sales.
During her stay in Ephesus, Laodice continued numerous intrigues to become queen again. By 246 BC Antiochus had left Berenice and their infant son Antiochus, in Antioch to live again with Laodice I in Asia Minor. Laodice took the occasion to poison Antiochus while her partisans at Antioch murdered Berenice and their infant son. Antiochus was buried in the Belevi Mausoleum.
Laodice I then proclaimed Seleucus II as King. With his cousin-wife Laodice I, Antiochus had two sons: Seleucus II Callinicus, Antiochus Hierax and three daughters: Apama, Stratonice of Cappadocia and Laodice.
Ashoka also claims that he encouraged the development of herbal medicine, for men and animals, in the territories of the Hellenistic kings: