Macatee was born in Rome, New York, and grew up in El Paso, Texas. He graduated from Burges High School in El Paso. In 1978, he earned a Bachelor of Science degree from Lamar University in Beaumont, Texas. He is a member of Delta Tau Delta International Fraternity.
While in college, Macatee worked at KLTV-TV in Tyler, Texas as well as KTVV-TV in Austin, Texas. He became Sports Director at KBMT-TV in Beaumont, Texas where he was hired by Bill Paradoski. Following that he worked at KMBC-TV in Kansas City before spending 3 years at WFAA-TV in Dallas, Texas. Macatee was hired by NBC Sports and moved to New York in 1982.
In 1982, Macatee began his network sports broadcasting career with NBC, and was the youngest network sportscaster in the industry. With NBC Sports, he covered a wide range of events including Wimbledon, the Super Bowl, the Rose Bowl and the World Series. He hosted NBC's Major League Baseball Game of the Week pre-game show for 4 years as well as numerous events for the network's sports anthology show, NBC Sportsworld. Additionally, Macatee served as the sports correspondent for the Today Show and sports anchor for NBC News at Sunrise and Sunday Today. He also co-anchored the syndicated show USA Today on TV.
Macatee joined USA Network as a sportscaster in 1990. From 1991 until 2006, Macatee anchored coverage of the PGA Tour and hosted the network's Thursday/Friday coverage of The Masters from Butler Cabin as well as coverage of the Ryder Cup. His other duties included play-by-play for the U.S. Open Tennis Championships and the French Open at Roland Garros.
Macatee served as an anchor during the 1998 Winter Olympics in Nagano, Japan for CBS and the 2006 Winter Games in Torino, Italy for USA Network.
Since joining CBS Sports in 1995, Macatee has served as a tower announcer and handled post-round, network interviews for The Masters and PGA Championship. Macatee also substitutes for Jim Nantz during other PGA Tour events and has anchored CBS' coverage of the LPGA Championship and various Champions Tour events. In 2015, Macatee hosted the Golf Channel series, Greatest Rounds.
From 1998 through 2013, Macatee did play-by-play for the NFL on CBS. He also called NCAA Basketball for CBS Sports including the NCAA Tournament and the NCAA Men's Division II Basketball National Championship Game. Macatee has done network play-by-play in sports as diverse as figure skating, skiing, track-and-field, gymnastics, boxing and even sumo wrestling.
Macatee co-anchored weekend coverage of the 1998 Winter Games in Nagano, Japan for CBS Sports and the 2006 Winter Olympics in Turin, Italy for NBC/USA Network.
Additionally, Macatee has served as the main play-by-play voice and studio host for the cable network Tennis Channel, covering the Australian Open, The French Open (French Open Tonight), Wimbledon (Wimbledon Primetime) and the U.S. Open.
In 2013, Macatee joined The Vistria Group, a Chicago private equity firm, serving as a Senior Advisor to the firm. Macatee serves on numerous company boards, as well as the Advisory Board of the United States Tennis Association (USTA) Foundation.
Macatee spent 2 years as an Adjunct Professor at Chapman University in Southern California, teaching Sports Media at the prestigious Dodge College of Film and Media Arts. Macatee serves as a Trustee at Lamar University. He was named Distinguished Alumnus at Lamar University in 2010 and gave the Commencement Address for the university's graduating class in May 2014.
In 2018, Macatee was inducted into the Texas Golf Hall of Fame receiving the Lifetime Achievement Award. 
On May 10, 2014, Macatee married Sonya Lee. They reside in Dallas, Texas.
He is also father to Caitlin Macatee, an up-and-coming comedian and author.