Eupatorium Perfoliatum
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Eupatorium Perfoliatum

Eupatorium perfoliatum
Eupatorium perfoliatum 001.JPG

Secure (NatureServe)[1]
Scientific classification edit
Kingdom: Plantae
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Asterales
Family: Asteraceae
Genus: Eupatorium
E. perfoliatum
Binomial name
Eupatorium perfoliatum
Eupatorium perfoliatum range map.jpg

Eupatorium perfoliatum, known as common boneset or just boneset, is a North American perennial plant in the aster family. It is a common native to the Eastern United States and Canada, widespread from Nova Scotia to Florida, west as far as Texas, Nebraska, the Dakotas, and Manitoba.[3][4] It is also called agueweed, feverwort, or sweating-plant. It was introduced to American colonists by natives who used the plant for breaking fevers by means of heavy sweating. It is nearly always found in low, wet areas.


E. perfoliatum can be recognized from its perfoliate leaves

Eupatorium perfoliatum grows up to 100 cm (39 inches) tall, with leaves that clasp the stems. The plant produces dense clusters of tiny white flower heads held above the foliage.

Eupatorium perfoliatum can form hybrids with other species of the genus Eupatorium, for example Eupatorium serotinum.[3]

Phytochemistry and safety

E. perfoliatum leaves and roots contain mixed phytochemicals, including polysaccharides (containing xylose and glucuronic acid), tannins, volatile oil, sesquiterpene lactones, sterols, triterpenes, alkaloids, and various flavonoids, such as quercetin, kaempferol, and caffeic acid derivatives.[5][6]E. perfoliatum and several of its related species are listed on the Poisonous Plants Database of the US Food and Drug Administration,[7] with E. perfoliatum described as an "unapproved homeopathic medicine" with unknown safety by the US National Library of Medicine.[5][8]

Traditional medicine

Eupatorium perfoliatum (also called boneset) was used in traditional medicine by Native Americans who applied extracts for fever and common colds.[5][6] Possible effects of E. perfoliatum for these uses remain undefined by adequate scientific research, and are unconfirmed by high-quality clinical research.[5][6] If consumed in large amounts, its tea made from leaves may cause diarrhea.[5]


Eupatorium perfoliatum is a specific butterfly food and habitat plant. It provides nectar for butterflies in the adult life cycle stage, particularly the white M hairstreak and the bronze copper butterfly.


  1. ^ "Eupatorium perfoliatum". NatureServe Explorer. NatureServe. Retrieved .
  2. ^ "Eupatorium perfoliatum L.". The Global Compositae Checklist (GCC) – via The Plant List.
  3. ^ a b Siripun, Kunsiri Chaw; Schilling, Edward E. (2006). "Eupatorium perfoliatum". In Flora of North America Editorial Committee (ed.). Flora of North America North of Mexico (FNA). 21. New York and Oxford – via, Missouri Botanical Garden, St. Louis, MO & Harvard University Herbaria, Cambridge, MA.
  4. ^ "Eupatorium perfoliatum". County-level distribution map from the North American Plant Atlas (NAPA). Biota of North America Program (BONAP). 2014.
  5. ^ a b c d e "Boneset (Eupatorium perfoliatum L.) Uses, Benefits and Dosage". 1 February 2019. Retrieved 2019.
  6. ^ a b c Hensel, Andreas; Maas, Mareike; Sendker, Jandirk; Lechtenberg, Matthias; Petereit, Frank; Deters, Alexandra; Schmidt, Thomas; Stark, Timo (2011). "Eupatorium perfoliatum L.: Phytochemistry, traditional use and current applications". Journal of Ethnopharmacology. 138 (3): 641-651. doi:10.1016/j.jep.2011.10.002. PMID 22004891.
  7. ^ "Flavonol-3-glucosides in 8 Eupatorium species; In: FDA Poisonous Plant Database". US Food and Drug Administration. 2019. Retrieved 2019.
  8. ^ "Eupatorium perfoliatum L." DailyMed, National Library of Medicine, US National Institutes of Health. 2019. Retrieved 2019.

External links

  This article uses material from the Wikipedia page available here. It is released under the Creative Commons Attribution-Share-Alike License 3.0.



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