Haemoglobinuria
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Haemoglobinuria
Hemoglobinuria
Other namesHaemoglobinuria
1GZX Haemoglobin.png
Structure of hemoglobin
SpecialtyUrology, nephrology

Hemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine.[1] The condition is often associated with any hemolytic anemia with primarily intravascular hemolysis, in which red blood cells (RBCs) are destroyed, thereby releasing free hemoglobin into the plasma. Excess hemoglobin is filtered by the kidneys, which excrete it into the urine, giving urine a purple color. Hemoglobinuria can lead to acute tubular necrosis which is an uncommon cause of a death of uni-traumatic patients recovering in the ICU .

Causes

Diagnosis

The diagnosis is often made based on the medical history, blood samples, and a urine sample. The absence of urine RBCs and RBC casts microscopically despite a positive dipstick test suggests hemoglobinuria or myoglobinuria. The medical term for RBCs in the urine is hematuria.

See also

References

  1. ^ Deters, A.; Kulozik, A. E. (2003). "Hemoglobinuria". Practical Algorithms in Pediatric Hematology and Oncology: 20-21. doi:10.1159/000069582. ISBN 3-8055-7432-0. Retrieved 2019.

External links



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Haemoglobinuria
 



 



 
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