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Heloise may refer to:
- Héloïse (1090-1164), French writer and abbess, lover of Peter Abelard
- Heloise (columnist) (Kiah Michelle Cruse, born 1951), American advice columnist, daughter of the original "Hints from Heloise" author
- Heloise Bowles Cruse (1919-1977), American advice columnist, the original author of "Hints from Heloise"
- Heloise (Jimmy Two-Shoes), a character on Canadian animated children's TV series Jimmy Two-Shoes
People with the given name
People with the surname