James S. Clegg
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James S. Clegg

James Standish Clegg (born 1933)[1] is a Professor Emeritus of Biochemistry at University of California, Davis,[3][5] based at the Coastal and Marine Sciences Institute (CMSI) in Bodega Bay, California.[4] He served as director of the Bodega Marine Laboratory (BML) from 1986 to 1999 and as president of the National Association Marine Laboratories (NAML) from 1991 to 1993.[6][7]


Clegg received his Bachelor of Science degree from Pennsylvania State University in Zoology in 1958[6] and his PhD from Johns Hopkins University in 1961 for research investigating the physiology of blood trehalose and its function during flight in the blowfly.[8][9]

Research and career

After his PhD, Clegg was a postdoctoral researcher with David R. Evans from 1961 to 1962.[10] At the National Institutes of Health (NIH) Clegg was a predoctoral fellow and postdoctoral fellow from 1960 to 1962.[6] He was a professor at University of Miami[11][12] from 1963 to 1986 and UC Davis from 1986.[13] He has been a visiting scientist at Oak Ridge National Laboratory (ORNL) in 1966, the Centre national de la recherche scientifique (CNRS, Paris), and University College of Wales in Aberystwyth, United Kingdom in 1990 and Ghent University in 1999.[6]

Clegg's research interests are biochemical and biophysical adaptations to environmental extremes (extremophiles); stress proteins and molecular chaperones in invertebrates; organization of enzymes and metabolic activity in the aqueous compartments of cells[14] and the physical properties of intracellular water.[3][6] His research used brine shrimp and Artemia salina as model organism.[7][12][11]

Awards and Honors

Clegg was awarded Phi Beta Kappa () from Pennsylvania State University in 1958. Clegg was a Woodrow Wilson fellow at the Johns Hopkins University from 1958 to 1959.[6] He was a Fulbright Program senior research fellow at the University of London in 1978 and again at Ghent University, Belgium in 1999. He was elected Fellow of the American Association for the Advancement of Science (FAAAS) in 1985.[6]


  1. ^ a b James S. Clegg at Library of Congress Authorities
  2. ^ Ancestry.com. U.S., Public Records Index, 1950-1993, Volume 2 [database on-line]. Lehi, UT, USA: Ancestry.com Operations, Inc., 2010. Voter Registration Lists, Public Record Filings, Historical Residential Records, and Other Household Database Listings.
  3. ^ a b c James S. Clegg publications indexed by Google Scholar Edit this at Wikidata
  4. ^ a b Clegg, James S. (2001). "Cryptobiosis -- a peculiar state of biological organization". Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 128 (4): 613-624. doi:10.1016/S1096-4959(01)00300-1. ISSN 1096-4959. PMID 11290443. closed access
  5. ^ James S. Clegg publications indexed by the Scopus bibliographic database. (subscription required)
  6. ^ a b c d e f g Anon (2018). "James S. Clegg: Emeritus Professor". biology.ucdavis.edu. University of California, Davis. Archived from the original on 2018-03-02.
  7. ^ a b Clegg, James S. (1997). "Embryos of Artemia franciscana survive four years of continuous anoxia: The case for complete metabolic rate depression". Journal of Experimental Biology. 200 (3): 467-475. PMID 9318130. Free to read
  8. ^ Clegg, James Standish (1961). The physiology of blood trehalose and its function during flight in the blowfly. jhu.edu (PhD thesis). Johns Hopkins University. OCLC 30555269.
  9. ^ Clegg, James S.; Evans, David R. (1961). "The Physiology of Blood Trehalose and its Function During Flight in the Blowfly". The Journal of Experimental Biology. The Company of Biologists. 38 (4): 771-792. Free to read
  10. ^ Clegg, James S.; Evans, David R. (1961). "Blood Trehalose and Flight Metabolism in the Blowfly". Science. 134 (3471): 54-55. Bibcode:1961Sci...134...54C. doi:10.1126/science.134.3471.54. ISSN 0036-8075. PMID 13694011. S2CID 35762256. closed access
  11. ^ a b Clegg, James S. (1964). "The Control of Emergence and Metabolism by External Osmotic Pressure and the Role of Free Glycerol in Developing Cysts of Artemia salina". Journal of Experimental Biology. 41 (4): 879-892. PMID 14239915. Free to read
  12. ^ a b Clegg, James S. (1965). "The origin of trehalose and its significance during the formation of encysted dormant embryos of Artemia salina". Comparative Biochemistry and Physiology. 14 (1): 135-143. doi:10.1016/0010-406X(65)90014-9. ISSN 0010-406X. PMID 14288194. closed access
  13. ^ Clegg, James; Kell, Douglas; Knull, Harvey; Welch, G.Rickey; Wilson, John (2001). "Macromolecular interactions: tracing the roots". Trends in Biochemical Sciences. 26 (2): 91. doi:10.1016/S0968-0004(00)01739-4. ISSN 0968-0004. PMID 11327044. closed access
  14. ^ Clegg, James S. (1984). "Properties and metabolism of the aqueous cytoplasm and its boundaries". American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 246 (2): R133-R151. doi:10.1152/ajpregu.1984.246.2.R133. ISSN 0363-6119. PMID 6364846. Free to read

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