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Rense's radio program and website propagate conspiracy theories, including those of 9/11 conspiracists,Ufologists and advocates of the paranormal, the creation of diseases, chemtrails, evidence of advanced ancient technology, emergent energy technologies, and alternative medicine.
Rense's first on-air experience came while he was a student at University of California, Santa Barbara. Some years later, in 1994, Rense self-financed a radio show on Santa Barbara's KTMS. The show was originally broadcast as Sightings on the Radio, the title being a direct reference to the television series Sightings. Around the year 2000, all references to Sightings were dropped and the current title was adopted.
The show was originally distributed by Premiere Radio Networks, but was dropped in the late 1990s due to being banned in Europe, being deemed hate speech. Talk Radio Network then carried the show through the early 2000s. Genesis Communications Network next took over distribution and carried the show through August 2009, until being dropped by the station after Rense accused fellow GCN host Alex Jones of threatening to "destroy" him.Jeff Rense Program is now streamed through Rense's personal website.
Recurring themes on Jeff Rense Program are a mistrust of the establishment and theorizing about who was behind the September 11 attacks. Regular guests include conspiracy theorists, geopolitical analysts, and ufologists. Guests have included former Congresswoman Cynthia McKinney, The Political Cesspools host James Edwards, paranormal expert Brad Steiger, the English former footballer and television presenter David Icke, Texe Marrs, and David Duke.