The main building was built in 1920s and belonged to the biologist Jakob von Uexküll. In 1949, after World War II, it became an official research station. It is known for ornithology research, especially bird ecophysiology and ecology.
Since 1977 Puhtu biology station belongs to Estonian University of Life Sciences.
Memorial stone of Eerik Kumari, the founder of the station.
Memorial to German poet Friedrich Schiller from 1813.