Route of US 52 in South Carolina highlighted in red
|Maintained by SCDOT|
|Length||159.7 mi (257.0 km)|
|South end||Line Street in Charleston|
|North end||at the North Carolina line near Cheraw|
|Counties||Charleston, Berkeley, Williamsburg, Florence, Darlington, Chesterfield|
U.S. Route 52 (US 52) is a 159.7-mile-long (257.0 km) north-south U.S. Highway that travels from Charleston to the North Carolina state line near Cheraw. It serves as a strategic highway through the central part of the state. Though an even-numbered U.S. Highway, which are typically signed east-west, it is signed north-south in South Carolina. In some other states along its route, it is signed east-west. The South Carolina segment is signed such that U.S. 52 north corresponds to the general westward direction of the highway, and vice versa.
US 52 begins at the intersection of Meeting and Line Streets, in Charleston. Going northwest along Meeting Street, it connects with I-26/US 17, followed by Morrison Drive (US 52 Spur hidden); US 52 signage begin to appear north of Morrison Drive. In North Charleston, it shares a concurrency with US 78 for 11 miles (18 km), splitting near Goose Creek. In Moncks Corner it connects with US 17 Alt briefly as it enters and traverses through Francis Marion National Forest. Continuing north, it goes through St. Stephen, Kingstree and Lake City, before joining another short concurrency with US 301 from Effingham to Florence. Through downtown Florence, it goes northwest and bypasses Darlington and joining another concurrency with US 401. At Society Hill, it merges briefly with US 15 before continuing north again solo to Cheraw, where it overlaps briefly with US 1 and SC 9. US 52 crosses the North Carolina state line, after traveling 159.7 miles (257.0 km) through South Carolina, continuing on towards Wadesboro.
US 52 is a major highway between Charleston and Florence, all of which is four-lane or more with some sections signed 60-mile-per-hour (97 km/h). North of Darlington, it becomes mostly a two-lane rural highway through the remainder of its route. Though the majority of its routing and signage is north-south, some sections will also be signed east-west at various parts of the state.
US 52 in South Carolina feature a few dedicated or memorialized stretches of freeway.
US 52 was established in 1935 as a renumbering of US 601 from the North Carolina state line to Florence and US 17 from Florence to Charleston. In 1939, US 52 was rerouted into a concurrency with US 78 in North Charleston, leaving a section of Meeting Street. Also in the same year, Cheraw to the North Carolina state line was the last section to be paved; while the first section of US 52 was widen to four-lane from Charleston to Durant Avenue, in North Charleston.
In 1940, US 52 was rerouted onto new alignment west of Lake City. In 1948, US 52 was taken off King Street and placed on Meeting Street to Lee Street, in Charleston. Around 1952-1969, US 52 was split during that period in Florence, with northbound along Irby Street and southboudn along Coit Avenue; before and after it was solely on Irby Street. Also around 1952, US 52 was bypassed west of Kingstree on new primary routing; the old route through town remained part of SC 261 while Academy Street, Kelly Street and Third Avenue were downgraded to secondary roads (all three SC-45-8).
In 1971, US 52 was moved onto new alignment south of Moncks Corner, leaving behind Old Highway 52 (S-8-791). By 1973, US 52 was placed on new primary routing bypassing west around Darlington, leaving behind US 52 Bus.
|Charleston||Charleston||0.0||0.0||Line Street||Southern terminus of US 52 (unmarked)|
|0.6||0.97||west / north - Mount Pleasant, North Charleston, Columbia||National east end of I-26, exit 221B|
south (Morrison Drive) to / Mount Pleasant Street
|No US 52 Spur signage at intersection|
|North Charleston||3.1||5.0||west - Columbia||I-26 exit 217. Northbound exit, southbound entrance; access to I-26 east via Spruill Avenue|
|4.3||6.9||east (Rivers Avenue)||East end of US 78 overlap|
|4.9||7.9||south (Cosgrove Avenue)|
|5.0||8.0||west (Dorchester Road) - Summerville|
|8.0||12.9||- Mount Pleasant, Savannah||I-526 exits 18A-B|
|12.7||20.4||east - Charleston||I-26 exit 209A; no northbound exit|
|14.2||22.9||west (University Avenue) / N.A.D. Road - Summerville||West end of US 78 overlap; to Charleston Southern University and Navel Weapons Station|
|Berkeley||Goose Creek||16.0||25.7||west (St. James Avenue) / Red Bank Road - Holly Hill|
|Moncks Corner||30.5||49.1||west (Main Street) - Holly Hill|
south (Live Oak Drive) - Summerville
|South end of US 17 Alt overlap|
|||33.0||53.1||To - Cordesville, Huger|
north - Georgetown
|North end of US 17 Alt overlap|
|St. Stephen||46.3||74.5||(Ravenell Drive) - Jamestown, Pineville|
|Williamsburg||||56.4||90.8||(Gourdin Road) - Gourdin, Greeleyville|
|||61.4||98.8||- Salters, Greeleyville|
|||68.4||110.1||north (Manning Highway) - Manning||North end of SC 261 overlap|
|Kingstree||71.0||114.3||south (Main Street) / south (Longstreet Street) - Andrews, Hemingway||South end of SC 261/SC 527 overlap|
|71.5||115.1||north (Academy Street) - Sumter||North end of SC 527 overlap|
|Cades||80.4||129.4||east / Cade Road - Cades, Hebron|
/ (Main Street) - Johnsonville, Olanta, Sumter
|87.9||141.5||- Conway, Sumter|
|Coward||93.3||150.2||west (Salem Road) - Olanta|
|Effingham||100.0||160.9||south (Olanta Highway) / north (Effingham Highway) - Evergreen, Olanta, Manning||South end of US 301 overlap|
|Florence||106.0||170.6||north (Freedom Boulevard) - Marion||North end of US 301 overlap|
|107.6||173.2||south (Pamplico Highway/Second Loop Road)|
|109.5||176.2||(Palmetto Street) - Marion, Timmonsville||To Francis Marion University|
|||112.8||181.5||- Fayetteville, Savannah||I-95 exit 164; to Myrtle Beach via I-95 and SC 327|
north (Main Street) - Darlington
|119.1||191.7||- Darlington, Timmonsville|
|119.7||192.6||south (Lamar Highway) - Sumter||South end of US 401 overlap|
|120.0||193.1||/ (Harry Byrd Highway) - Hartsville, Darlington, Charlotte||Interchange|
south (Main Street) - Darlington
|||134.0||215.7||south (Hartsville Highway) - Hartsville||South end of US 15 overlap|
|Society Hill||136.2||219.2||north / north (Main Street) - Bennettsville||North end of US 15/US 401 overlap|
|Chesterfield||||147.2||236.9||- McBee, Camden||South end of US 1 overlap|
|Cheraw||149.6||240.8||north (Market Street) - Chesterfield||North end of SC 9 overlap|
|150.9||242.9||north / south (Power Street) - Wallace, Bennettsville, Rockingham||North end of US 1 and south end of SC 9 overlap|
|||159.7||257.0||north - Wadesboro||Continuation into North Carolina|
|1.000 mi = 1.609 km; 1.000 km = 0.621 mi|