|1972 St. Louis Cardinals season|
|Head coach||Bob Hollway|
|Home field||Busch Memorial Stadium|
|Division place||4th NFC East|
|Playoff finish||Did not qualify|
The 1972 St. Louis Cardinals season was the team's 53rd year with the National Football League and thirteenth in St. Louis. On September 2, Bill Bidwill purchased the stock of his brother Charles "Stormy" Bidwill to become sole owner of the Cardinals. The adopted sons of Charles and Violet Bidwill, the two had co-owned the team since their mother's death in January 1962.
After starting at 2-2, with wins over 1970 and 1971 playoff participants Baltimore and Minnesota, the Cardinals went 0-7-1, then won their final two games over the Rams and Eagles to finish at 4-9-1 for the second consecutive season and third time in the past four. Second-year head coach Bob Hollway was fired December 18, the day after the regular season finale, succeeded a month later by San Diego State head coach Don Coryell.
|1||September 17||at Baltimore Colts||W 10-3||1-0||Memorial Stadium||53,652|
|2||September 24||at Washington Redskins||L 10-24||1-1||RFK Stadium||53,039|
|3||October 1||Pittsburgh Steelers||L 19-25||1-2||Busch Memorial Stadium||49,140|
|4||October 8||at Minnesota Vikings||W 19-17||2-2||Metropolitan Stadium||49,687|
|5||October 15||Washington Redskins||L 3-33||2-3||Busch Memorial Stadium||50,454|
|6||October 22||at New York Giants||L 21-27||2-4||Yankee Stadium||62,756|
|7||October 29||Chicago Bears||L 10-27||2-5||Busch Memorial Stadium||50,464|
|8||November 5||at Philadelphia Eagles||T 6-6||2-5-1||Veterans Stadium||65,720|
|9||November 12||at Dallas Cowboys||L 24-33||2-6-1||Texas Stadium||65,218|
|10||November 19||New York Giants||L 7-13||2-7-1||Busch Memorial Stadium||48,014|
|11||at Miami Dolphins||L 10-31||2-8-1||Miami Orange Bowl||80,010|
|12||December 3||Dallas Cowboys||L 6-27||2-9-1||Busch Memorial Stadium||49,787|
|13||December 10||Los Angeles Rams||W 24-14||3-9-1||Busch Memorial Stadium||36,873|
|14||December 17||Philadelphia Eagles||W 24-23||4-9-1||Busch Memorial Stadium||34,872|
Note: Intra-division opponents are in bold text.
|New York Giants||8||6||0||.571||5-3||7-4||331||247||W1|
|St. Louis Cardinals||4||9||1||.321||1-6-1||3-7-1||193||303||W2|