|King of Bithynia|
|Reign||149 - 127 BC|
Nicomedes II Epiphanes (Greek: ? "Nicomedes God-Manifest") was the king of Bithynia from 149 to c. 127 BC. He was fourth in descent from Nicomedes I. Nicomedes II was the son and successor of Prusias II and Apame IV. His parents were related as they were maternal cousins.
He was so popular with the people that his father sent him to Rome to limit his influence. However, in Rome, he also gained favor from the Roman Senate, forcing Prusias to send an emissary named Menas with secret orders to assassinate him. But the emissary revealed the plot, and persuaded the prince to rebel against his father.
Supported by Attalus II Philadelphus, king of Pergamon, he was completely successful, and ordered his father to be put to death at Nicomedia. During his long reign Nicomedes adhered steadily to the Roman alliance, and assisted them against the pretender to the throne of Pergamon Eumenes III. He was succeeded by his son Nicomedes III.
He sent Menas as his fellow ambassador, and told him if he should secure a remission of the payments to spare Nicomedes, but if not, to kill him at Rome.
Prusias fled to the temple of Zeus, where he was stabbed by some of the emissaries of Nicomedes.